IntAct: A nondisruptive internal tagging strategy to study the organization and function of actin is...
IntAct: A nondisruptive internal tagging strategy to study the organization and function of actin isoforms
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Mammals have 6 highly conserved actin isoforms with nonredundant biological functions. The molecular basis of isoform specificity, however, remains elusive due to a lack of tools. Here, we describe the development of IntAct, an internal tagging strategy to study actin isoforms in fixed and living cells. We identified a residue pair in β-actin that...
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Full title
IntAct: A nondisruptive internal tagging strategy to study the organization and function of actin isoforms
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TN_cdi_plos_journals_3069178757
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069178757
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.3002551
