Review and further developments in statistical corrections for Winner’s Curse in genetic association...
Review and further developments in statistical corrections for Winner’s Curse in genetic association studies
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Genome-wide association studies (GWAS) are commonly used to identify genomic variants that are associated with complex traits, and estimate the magnitude of this association for each variant. However, it has been widely observed that the association estimates of variants tend to be lower in a replication study than in the study that discovered thos...
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Review and further developments in statistical corrections for Winner’s Curse in genetic association studies
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TN_cdi_plos_journals_3069179265
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069179265
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1010546
