PGP-14 establishes a polar lipid permeability barrier within the C. elegans pharyngeal cuticle
PGP-14 establishes a polar lipid permeability barrier within the C. elegans pharyngeal cuticle
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The cuticles of ecdysozoan animals are barriers to material loss and xenobiotic insult. Key to this barrier is lipid content, the establishment of which is poorly understood. Here, we show that the p-glycoprotein PGP-14 functions coincidently with the sphingomyelin synthase SMS-5 to establish a polar lipid barrier within the pharyngeal cuticle of t...
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Full title
PGP-14 establishes a polar lipid permeability barrier within the C. elegans pharyngeal cuticle
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TN_cdi_plos_journals_3069179427
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069179427
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ISSN
1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1011008
