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Mechanistic insight into the functional role of human sinoatrial node conduction pathways and pacema...

Mechanistic insight into the functional role of human sinoatrial node conduction pathways and pacema...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069179487

Mechanistic insight into the functional role of human sinoatrial node conduction pathways and pacemaker compartments heterogeneity: A computer model analysis

About this item

Full title

Mechanistic insight into the functional role of human sinoatrial node conduction pathways and pacemaker compartments heterogeneity: A computer model analysis

Publisher

United States: Public Library of Science

Journal title

PLoS computational biology, 2023-12, Vol.19 (12), p.e1011708-e1011708

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The sinoatrial node (SAN), the primary pacemaker of the heart, is responsible for the initiation and robust regulation of sinus rhythm. 3D mapping studies of the ex-vivo human heart suggested that the robust regulation of sinus rhythm relies on specialized fibrotically-insulated pacemaker compartments (head, center and tail) with heterogeneous expr...

Alternative Titles

Full title

Mechanistic insight into the functional role of human sinoatrial node conduction pathways and pacemaker compartments heterogeneity: A computer model analysis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3069179487

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069179487

Other Identifiers

ISSN

1553-7358,1553-734X

E-ISSN

1553-7358

DOI

10.1371/journal.pcbi.1011708

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