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The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its...

The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069179811

The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its sheddase activity

About this item

Full title

The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its sheddase activity

Publisher

San Francisco: Public Library of Science

Journal title

PLoS pathogens, 2023-11, Vol.19 (11), p.e1011759-e1011759

Language

English

Formats

Publication information

Publisher

San Francisco: Public Library of Science

More information

Scope and Contents

Contents

Hepatitis C virus (HCV) exploits the four entry factors CD81, scavenger receptor class B type I (SR-BI, also known as SCARB1), occludin, and claudin-1 as well as the co-factor epidermal growth factor receptor (EGFR) to infect human hepatocytes. Here, we report that the disintegrin and matrix metalloproteinase 10 (ADAM10) associates with CD81, SR-BI...

Alternative Titles

Full title

The matrix metalloproteinase ADAM10 supports hepatitis C virus entry and cell-to-cell spread via its sheddase activity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3069179811

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069179811

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1011759

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