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Virally encoded interleukin-6 facilitates KSHV replication in monocytes and induction of dysfunction...

Virally encoded interleukin-6 facilitates KSHV replication in monocytes and induction of dysfunction...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069180185

Virally encoded interleukin-6 facilitates KSHV replication in monocytes and induction of dysfunctional macrophages

About this item

Full title

Virally encoded interleukin-6 facilitates KSHV replication in monocytes and induction of dysfunctional macrophages

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2023-10, Vol.19 (10), p.e1011703-e1011703

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic double-stranded DNA virus and the etiologic agent of Kaposi’s sarcoma and hyperinflammatory lymphoproliferative disorders. Understanding the mechanism by which KSHV increases the infected cell population is crucial for curing KSHV-associated diseases. Using scRNA-seq, we demonstrate tha...

Alternative Titles

Full title

Virally encoded interleukin-6 facilitates KSHV replication in monocytes and induction of dysfunctional macrophages

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3069180185

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069180185

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1011703

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