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High-sensitivity analysis of clonal hematopoiesis reveals increased clonal complexity of potential-d...

High-sensitivity analysis of clonal hematopoiesis reveals increased clonal complexity of potential-d...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069214040

High-sensitivity analysis of clonal hematopoiesis reveals increased clonal complexity of potential-driver mutations in severe COVID-19 patients

About this item

Full title

High-sensitivity analysis of clonal hematopoiesis reveals increased clonal complexity of potential-driver mutations in severe COVID-19 patients

Publisher

United States: Public Library of Science

Journal title

PloS one, 2024-01, Vol.19 (1), p.e0282546-e0282546

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Whether Clonal Hematopoiesis (CH) represents a risk factor for severity of the COVID-19 disease remains a controversial issue. We report the first high- sensitivity analysis of CH in COVID-19 patients (threshold of detection at 0.5% vs 1 or 2% in previous studies). We analyzed 24 patients admitted to ICU for COVID-19 (COV-ICU) and 19 controls, incl...

Alternative Titles

Full title

High-sensitivity analysis of clonal hematopoiesis reveals increased clonal complexity of potential-driver mutations in severe COVID-19 patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3069214040

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069214040

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0282546

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