SRC-1 controls growth cone polarity and protrusion with the UNC-6/Netrin receptor UNC-5 in Caenorhab...
SRC-1 controls growth cone polarity and protrusion with the UNC-6/Netrin receptor UNC-5 in Caenorhabditis elegans
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The Polarity/Protusion model of UNC-6/Netrin function in axon repulsion does not rely on a gradient of UNC-6/Netrin. Instead, the UNC-5 receptor polarizes the VD growth cone such that filopodial protrusions are biased to the dorsal leading edge. UNC-5 then inhibits growth cone protrusion ventrally based upon this polarity, resulting in dorsally-bia...
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Full title
SRC-1 controls growth cone polarity and protrusion with the UNC-6/Netrin receptor UNC-5 in Caenorhabditis elegans
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TN_cdi_plos_journals_3069289238
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3069289238
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0295701
