UGT1A43 polymorphism influences serum concentration and therapeutic effect of lamotrigine for epilep...
UGT1A43 polymorphism influences serum concentration and therapeutic effect of lamotrigine for epilepsy treatment: A meta-analysis
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Lamotrigine as a broad-spectrum antiepileptic drug, is widely applied and its clinical efficacy is highly recognized. However, significant differences are observed in blood drug concentration of lamotrigine among individuals, which may have an impact on its efficacy. UGT1A4 is the main metabolic enzyme. However, it was inconsistent for the influenc...
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UGT1A43 polymorphism influences serum concentration and therapeutic effect of lamotrigine for epilepsy treatment: A meta-analysis
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TN_cdi_plos_journals_3082558176
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3082558176
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0307377
