Widespread fungal-bacterial competition for magnesium lowers bacterial susceptibility to polymyxin a...
Widespread fungal-bacterial competition for magnesium lowers bacterial susceptibility to polymyxin antibiotics
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Fungi and bacteria coexist in many polymicrobial communities, yet the molecular basis of their interactions remains poorly understood. Here, we show that the fungus Candida albicans sequesters essential magnesium ions from the bacterium Pseudomonas aeruginosa. To counteract fungal Mg2+ sequestration, P. aeruginosa expresses the Mg2+ transporter Mgt...
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Widespread fungal-bacterial competition for magnesium lowers bacterial susceptibility to polymyxin antibiotics
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TN_cdi_plos_journals_3086942150
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3086942150
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ISSN
1545-7885,1544-9173
E-ISSN
1545-7885
DOI
10.1371/journal.pbio.3002694