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An eQTL-based approach reveals candidate regulators of LINE-1 RNA levels in lymphoblastoid cells

An eQTL-based approach reveals candidate regulators of LINE-1 RNA levels in lymphoblastoid cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3086942698

An eQTL-based approach reveals candidate regulators of LINE-1 RNA levels in lymphoblastoid cells

About this item

Full title

An eQTL-based approach reveals candidate regulators of LINE-1 RNA levels in lymphoblastoid cells

Publisher

United States: Public Library of Science

Journal title

PLoS genetics, 2024-06, Vol.20 (6), p.e1011311

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Long interspersed element 1 (LINE-1; L1) are a family of transposons that occupy ~17% of the human genome. Though a small number of L1 copies remain capable of autonomous transposition, the overwhelming majority of copies are degenerate and immobile. Nevertheless, both mobile and immobile L1s can exert pleiotropic effects (promoting genome instabil...

Alternative Titles

Full title

An eQTL-based approach reveals candidate regulators of LINE-1 RNA levels in lymphoblastoid cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3086942698

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3086942698

Other Identifiers

ISSN

1553-7404,1553-7390

E-ISSN

1553-7404

DOI

10.1371/journal.pgen.1011311

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