Norwegian moose CWD induces clinical disease and neuroinvasion in gene-targeted mice expressing cerv...
Norwegian moose CWD induces clinical disease and neuroinvasion in gene-targeted mice expressing cervid S138N prion protein
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Publisher
United States: Public Library of Science
Journal title
Language
English
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Publisher
United States: Public Library of Science
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Contents
Chronic wasting disease (CWD) is a prion disease affecting deer, elk and moose in North America and reindeer, moose and red deer in Northern Europe. Pathogenesis is driven by the accumulation of PrP
Sc
, a pathological form of the host’s cellular prion protein (PrP
C
), in the brain. CWD is contagious among North American cervids and No...
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Full title
Norwegian moose CWD induces clinical disease and neuroinvasion in gene-targeted mice expressing cervid S138N prion protein
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TN_cdi_plos_journals_3086953168
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3086953168
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1012350
