Epstein-Barr virus protein EBNA-LP engages YY1 through leucine-rich motifs to promote naïve B cell t...
Epstein-Barr virus protein EBNA-LP engages YY1 through leucine-rich motifs to promote naïve B cell transformation
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Epstein-Barr Virus (EBV) is associated with numerous cancers including B cell lymphomas.
In vitro
, EBV transforms primary B cells into immortalized Lymphoblastoid Cell Lines (LCLs) which serves as a model to study the role of viral proteins in EBV malignancies. EBV induced cellular transformation is driven by viral proteins including EBV-Nuc...
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Full title
Epstein-Barr virus protein EBNA-LP engages YY1 through leucine-rich motifs to promote naïve B cell transformation
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TN_cdi_plos_journals_3086958574
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3086958574
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1011950