The lipopeptide Pam3CSK4 inhibits Rift Valley fever virus infection and protects from encephalitis
The lipopeptide Pam3CSK4 inhibits Rift Valley fever virus infection and protects from encephalitis
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Rift Valley fever virus (RVFV) is an encephalitic bunyavirus that can infect neurons in the brain. There are no approved therapeutics that can protect from RVFV encephalitis. Innate immunity, the first line of defense against infection, canonically antagonizes viruses through interferon signaling. We found that interferons did not efficiently prote...
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Full title
The lipopeptide Pam3CSK4 inhibits Rift Valley fever virus infection and protects from encephalitis
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TN_cdi_plos_journals_3086958606
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3086958606
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1012343