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The lipopeptide Pam3CSK4 inhibits Rift Valley fever virus infection and protects from encephalitis

The lipopeptide Pam3CSK4 inhibits Rift Valley fever virus infection and protects from encephalitis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3086958606

The lipopeptide Pam3CSK4 inhibits Rift Valley fever virus infection and protects from encephalitis

About this item

Full title

The lipopeptide Pam3CSK4 inhibits Rift Valley fever virus infection and protects from encephalitis

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2024-06, Vol.20 (6), p.e1012343

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Rift Valley fever virus (RVFV) is an encephalitic bunyavirus that can infect neurons in the brain. There are no approved therapeutics that can protect from RVFV encephalitis. Innate immunity, the first line of defense against infection, canonically antagonizes viruses through interferon signaling. We found that interferons did not efficiently prote...

Alternative Titles

Full title

The lipopeptide Pam3CSK4 inhibits Rift Valley fever virus infection and protects from encephalitis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3086958606

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3086958606

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1012343

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