Rapid and efficient generation of mature retinal organoids derived from human pluripotent stem cells...
Rapid and efficient generation of mature retinal organoids derived from human pluripotent stem cells via optimized pharmacological modulation of Sonic hedgehog, activin A, and retinoic acid signal transduction
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Human retinal organoids have become indispensable tools for retinal disease modeling and drug screening. Despite its versatile applications, the long timeframe for their differentiation and maturation limits the throughput of such research. Here, we successfully shortened this timeframe by accelerating human retinal organoid development using uniqu...
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Rapid and efficient generation of mature retinal organoids derived from human pluripotent stem cells via optimized pharmacological modulation of Sonic hedgehog, activin A, and retinoic acid signal transduction
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TN_cdi_plos_journals_3091107465
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3091107465
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0308743