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Rapid and efficient generation of mature retinal organoids derived from human pluripotent stem cells...

Rapid and efficient generation of mature retinal organoids derived from human pluripotent stem cells...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3091107465

Rapid and efficient generation of mature retinal organoids derived from human pluripotent stem cells via optimized pharmacological modulation of Sonic hedgehog, activin A, and retinoic acid signal transduction

About this item

Full title

Rapid and efficient generation of mature retinal organoids derived from human pluripotent stem cells via optimized pharmacological modulation of Sonic hedgehog, activin A, and retinoic acid signal transduction

Publisher

United States: Public Library of Science

Journal title

PloS one, 2024-08, Vol.19 (8), p.e0308743

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Human retinal organoids have become indispensable tools for retinal disease modeling and drug screening. Despite its versatile applications, the long timeframe for their differentiation and maturation limits the throughput of such research. Here, we successfully shortened this timeframe by accelerating human retinal organoid development using uniqu...

Alternative Titles

Full title

Rapid and efficient generation of mature retinal organoids derived from human pluripotent stem cells via optimized pharmacological modulation of Sonic hedgehog, activin A, and retinoic acid signal transduction

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3091107465

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3091107465

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0308743

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