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Changes in the analgesic mechanism of oxytocin can contribute to hyperalgesia in Parkinson’s disease...

Changes in the analgesic mechanism of oxytocin can contribute to hyperalgesia in Parkinson’s disease...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3095080913

Changes in the analgesic mechanism of oxytocin can contribute to hyperalgesia in Parkinson’s disease model rats

About this item

Full title

Changes in the analgesic mechanism of oxytocin can contribute to hyperalgesia in Parkinson’s disease model rats

Publisher

United States: Public Library of Science

Journal title

PloS one, 2024-08, Vol.19 (8), p.e0300081

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Pain is a major non-motor symptom of Parkinson’s disease (PD). Alterations in the descending pain inhibitory system (DPIS) have been reported to trigger hyperalgesia in PD patients. However, the underlying mechanisms remain unclear. In the current study, dopaminergic nigrostriatal lesions were induced in rats by injecting 6-hydroxydopamine (6-OHDA)...

Alternative Titles

Full title

Changes in the analgesic mechanism of oxytocin can contribute to hyperalgesia in Parkinson’s disease model rats

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3095080913

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3095080913

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0300081

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