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Identification and quantification of the molecular species of bilirubin BDG, BMG and UCB by LC‒MS/MS...

Identification and quantification of the molecular species of bilirubin BDG, BMG and UCB by LC‒MS/MS...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3130599309

Identification and quantification of the molecular species of bilirubin BDG, BMG and UCB by LC‒MS/MS in hyperbilirubinemic human serum

About this item

Full title

Identification and quantification of the molecular species of bilirubin BDG, BMG and UCB by LC‒MS/MS in hyperbilirubinemic human serum

Publisher

United States: Public Library of Science

Journal title

PloS one, 2024-11, Vol.19 (11), p.e0313044

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Unconjugated bilirubin (UCB) is a byproduct of the heme group that indicates irregularities in the metabolism of several important biological molecules, such as hemoglobin. UCB is processed by hepatic UGT1A1, which catalyzes its conjugation to the metabolites bilirubin diglucuronide (BDG) and bilirubin monoglucuronide (BMG). The serum concentration...

Alternative Titles

Full title

Identification and quantification of the molecular species of bilirubin BDG, BMG and UCB by LC‒MS/MS in hyperbilirubinemic human serum

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3130599309

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3130599309

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0313044

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