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Protease-activated receptor 2 deficient mice develop less angiotensin II induced left ventricular hy...

Protease-activated receptor 2 deficient mice develop less angiotensin II induced left ventricular hy...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3141380269

Protease-activated receptor 2 deficient mice develop less angiotensin II induced left ventricular hypertrophy but more cardiac fibrosis

About this item

Full title

Protease-activated receptor 2 deficient mice develop less angiotensin II induced left ventricular hypertrophy but more cardiac fibrosis

Publisher

United States: Public Library of Science

Journal title

PloS one, 2024-12, Vol.19 (12), p.e0310095

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Activation of Protease Activated Receptor 2 (PAR2) has been shown to be involved in regulation of injury-related processes including inflammation, fibrosis and hypertrophy. In this study we will investigate the role of PAR2 in cardiac injury in a mouse model of hypertension using continuous infusion with angiotensin II.
Hypertension was induced...

Alternative Titles

Full title

Protease-activated receptor 2 deficient mice develop less angiotensin II induced left ventricular hypertrophy but more cardiac fibrosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3141380269

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3141380269

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0310095

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