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A replication-incompetent adenoviral vector encoding for HSV-2 gD2 is immunogenic and protective aga...

A replication-incompetent adenoviral vector encoding for HSV-2 gD2 is immunogenic and protective aga...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3150493726

A replication-incompetent adenoviral vector encoding for HSV-2 gD2 is immunogenic and protective against HSV-2 intravaginal challenge in mice

About this item

Full title

A replication-incompetent adenoviral vector encoding for HSV-2 gD2 is immunogenic and protective against HSV-2 intravaginal challenge in mice

Publisher

United States: Public Library of Science

Journal title

PloS one, 2024-12, Vol.19 (12), p.e0310250

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Herpes Simplex virus (HSV) is the cause of genital herpes and no prophylactic treatment is currently available. Replication-incompetent adenoviral vectors are potent inducers of humoral and cellular immune responses in humans. We have designed an adenoviral vector type 35 (Ad35)-based vaccine encoding the HSV-2 major surface antigen gD2 (Ad35.HSV.g...

Alternative Titles

Full title

A replication-incompetent adenoviral vector encoding for HSV-2 gD2 is immunogenic and protective against HSV-2 intravaginal challenge in mice

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3150493726

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3150493726

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0310250

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