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Matrix metalloproteinase-12 by M2 macrophages induced epithelial to mesenchymal transition in chroni...

Matrix metalloproteinase-12 by M2 macrophages induced epithelial to mesenchymal transition in chroni...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3150493730

Matrix metalloproteinase-12 by M2 macrophages induced epithelial to mesenchymal transition in chronic rhinosinusitis with nasal polyps

About this item

Full title

Matrix metalloproteinase-12 by M2 macrophages induced epithelial to mesenchymal transition in chronic rhinosinusitis with nasal polyps

Publisher

United States: Public Library of Science

Journal title

PloS one, 2024-12, Vol.19 (12), p.e0313097

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Th2 inflammation and epithelial-mesenchymal transition (EMT) play crucial roles in the pathophysiology of chronic rhinosinusitis with nasal polyps (CRSwNP). This study aimed to investigate the hypothesis that MMP-12, produced by M2 macrophages, induces EMT in nasal epithelial cells, thereby contributing to airway inflammation and remodeling in CRSw...

Alternative Titles

Full title

Matrix metalloproteinase-12 by M2 macrophages induced epithelial to mesenchymal transition in chronic rhinosinusitis with nasal polyps

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3150493730

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3150493730

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0313097

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