Mechanism of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate
Mechanism of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Gap junction intercellular communication (GJIC) between two adjacent cells involves direct exchange of cytosolic ions and small molecules via connexin gap junction channels (GJCs). Connexin GJCs have emerged as drug targets, with small molecule connexin inhibitors considered a viable therapeutic strategy in several diseases. The molecular mechanism...
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Full title
Mechanism of connexin channel inhibition by mefloquine and 2-aminoethoxydiphenyl borate
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TN_cdi_plos_journals_3150493776
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3150493776
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0315510
