miRNA-328-3p regulates ZO-1 expression and inhibits PEDV proliferation via the PLC-β1-PKC pathway
miRNA-328-3p regulates ZO-1 expression and inhibits PEDV proliferation via the PLC-β1-PKC pathway
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Zhao, Han , Zhang, Jiayu , Li, Dengliang , Cui, Zhanding , Liu, Jiuyuan , Bao, Di , Wei, Yiming , Zhang, Xinyue , Wu, Zhimin , Zhang, Tianqi , Wang, Kai , Yi, Shushuai , Lian, Wei and Hu, Guixue
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Porcine epidemic diarrhea virus (PEDV) is a significant pathogen affecting swine, causing severe economic losses worldwide. This study explores the regulatory role of miRNA-328-3p to ZO-1 expression and its impact on PEDV proliferation via the PLC-β1-PKC pathway in IPEC-J2 cells. We found that miRNA-328-3p can target ZO-1, influencing its expressio...
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Full title
miRNA-328-3p regulates ZO-1 expression and inhibits PEDV proliferation via the PLC-β1-PKC pathway
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TN_cdi_plos_journals_3151369582
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3151369582
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0316074