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Therapeutic blockade of CCL17 in obesity-exacerbated osteoarthritic pain and disease

Therapeutic blockade of CCL17 in obesity-exacerbated osteoarthritic pain and disease

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3156421473

Therapeutic blockade of CCL17 in obesity-exacerbated osteoarthritic pain and disease

About this item

Full title

Therapeutic blockade of CCL17 in obesity-exacerbated osteoarthritic pain and disease

Publisher

United States: Public Library of Science

Journal title

PloS one, 2025-01, Vol.20 (1), p.e0317399

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

We previously reported that CCL17 gene-deficient mice are protected from developing pain-like behaviour and exhibit less disease in destabilization of medial meniscus (DMM)-induced OA, as well as in high-fat diet (HFD)-exacerbated DMM-induced OA. Here, we explored if therapeutic neutralization of CCL17, using increasing doses of a neutralizing mono...

Alternative Titles

Full title

Therapeutic blockade of CCL17 in obesity-exacerbated osteoarthritic pain and disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3156421473

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3156421473

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0317399

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