Exploration of small molecules as inhibitors of potential BACE1 protein to treat amyloid cerebrovasc...
Exploration of small molecules as inhibitors of potential BACE1 protein to treat amyloid cerebrovascular disease by employing molecular modeling and simulation approaches
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Amyloid cerebrovascular disease, primarily driven by the accumulation of amyloid-beta (Aβ) peptides, is intricately linked to neurodegenerative disorders like Alzheimer’s disease. BACE1 (beta-site amyloid precursor protein cleaving enzyme 1) plays a critical role in the production of Aβ, making it a key therapeutic target. In the current work, a CN...
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Exploration of small molecules as inhibitors of potential BACE1 protein to treat amyloid cerebrovascular disease by employing molecular modeling and simulation approaches
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TN_cdi_plos_journals_3180166110
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3180166110
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0317716
