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Silencing NRF2 enhances arsenic trioxide-induced ferroptosis in hepatocellular carcinoma cells

Silencing NRF2 enhances arsenic trioxide-induced ferroptosis in hepatocellular carcinoma cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3206832546

Silencing NRF2 enhances arsenic trioxide-induced ferroptosis in hepatocellular carcinoma cells

About this item

Full title

Silencing NRF2 enhances arsenic trioxide-induced ferroptosis in hepatocellular carcinoma cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2025-05, Vol.20 (5), p.e0322746

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide, with high mortality rates partially due to limited therapeutic options and drug resistance. Arsenic trioxide (ATO), a compound clinically proven for acute promyelocytic leukemia (APL), has garnered attention for its emerging efficacy in solid tumors, including HCC...

Alternative Titles

Full title

Silencing NRF2 enhances arsenic trioxide-induced ferroptosis in hepatocellular carcinoma cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_3206832546

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3206832546

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0322746

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