Silencing NRF2 enhances arsenic trioxide-induced ferroptosis in hepatocellular carcinoma cells
Silencing NRF2 enhances arsenic trioxide-induced ferroptosis in hepatocellular carcinoma cells
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Author / Creator
Huang, Mi , Li, Duanzhuo , Xia, Zhengzhen , Liao, Shengjie , Si, Wenxia , Yuan, Chao , Liao, Yanli , Wu, Weibin , Jiang, Minshu , Yu, Xin and Quan, Yi
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide, with high mortality rates partially due to limited therapeutic options and drug resistance. Arsenic trioxide (ATO), a compound clinically proven for acute promyelocytic leukemia (APL), has garnered attention for its emerging efficacy in solid tumors, including HCC...
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Full title
Silencing NRF2 enhances arsenic trioxide-induced ferroptosis in hepatocellular carcinoma cells
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TN_cdi_plos_journals_3206832546
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_3206832546
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0322746