Transcription Factor JunD, Deprived of Menin, Switches from Growth Suppressor to Growth Promoter
Transcription Factor JunD, Deprived of Menin, Switches from Growth Suppressor to Growth Promoter
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Different components of the AP1 transcription factor complex appear to have distinct effects on cell proliferation and transformation. In contrast to other AP1 components, JunD has been shown to inhibit cell proliferation. Also, in prior studies, JunD alone bound menin, product of the MEN1 tumor suppressor gene, and JunD's transcriptional activity...
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Transcription Factor JunD, Deprived of Menin, Switches from Growth Suppressor to Growth Promoter
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TN_cdi_pnas_primary_100_19_10770_fulltext
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_100_19_10770_fulltext
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1834524100
