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Redox Regulation of Surface Protein Thiols: Identification of Integrin α-4 as a Molecular Target by...

Redox Regulation of Surface Protein Thiols: Identification of Integrin α-4 as a Molecular Target by...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_100_25_14737_fulltext

Redox Regulation of Surface Protein Thiols: Identification of Integrin α-4 as a Molecular Target by Using Redox Proteomics

About this item

Full title

Redox Regulation of Surface Protein Thiols: Identification of Integrin α-4 as a Molecular Target by Using Redox Proteomics

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2003-12, Vol.100 (25), p.14737-14741

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Thiols affect a variety of cell functions, an effect known as redox regulation. We show here that treatment (1-2 h) of cells with 0.1-5 mM N-acetyl-L-cysteine (NAC) increases surface protein thiol expression in human peripheral blood mononuclear cells. This effect is not associated with changes in cellular glutathione (GSH) and is also observed wit...

Alternative Titles

Full title

Redox Regulation of Surface Protein Thiols: Identification of Integrin α-4 as a Molecular Target by Using Redox Proteomics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_100_25_14737_fulltext

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_100_25_14737_fulltext

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.2434516100

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