Ghrelin Stimulation of Growth Hormone Release and Appetite Is Mediated through the Growth Hormone Se...
Ghrelin Stimulation of Growth Hormone Release and Appetite Is Mediated through the Growth Hormone Secretagogue Receptor
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Synthetic agonists of the growth hormone secretagogue receptor (GHSR) rejuvenate the pulsatile pattern of GH-release in the elderly, and increase lean but not fat mass in obese subjects. Screening of tissue extracts in a cell line engineered to overexpress the GHSR led to the identification of a natural agonist called ghrelin. Paradoxically, this h...
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Full title
Ghrelin Stimulation of Growth Hormone Release and Appetite Is Mediated through the Growth Hormone Secretagogue Receptor
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TN_cdi_pnas_primary_101_13_4679
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_101_13_4679
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0305930101