Reversible Oxidation and Inactivation of the Tumor Suppressor PTEN in Cells Stimulated with Peptide...
Reversible Oxidation and Inactivation of the Tumor Suppressor PTEN in Cells Stimulated with Peptide Growth Factors
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Stimulation of cells with various peptide growth factors induces the production of phosphatidylinositol 3,4,5-trisphosphate ( PIP3) through activation of phosphatidylinositol 3-kinase. The action of this enzyme is reversed by that of the tumor suppressor PTEN. With the use of cells overexpressing NADPH oxidase 1 or peroxiredoxin II, we have now sho...
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Full title
Reversible Oxidation and Inactivation of the Tumor Suppressor PTEN in Cells Stimulated with Peptide Growth Factors
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TN_cdi_pnas_primary_101_47_16419
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_101_47_16419
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0407396101
