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Pathogen Effector Protein Screening in Yeast Identifies Legionella Factors That Interfere with Membr...

Pathogen Effector Protein Screening in Yeast Identifies Legionella Factors That Interfere with Membr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_102_13_4866_fulltext

Pathogen Effector Protein Screening in Yeast Identifies Legionella Factors That Interfere with Membrane Trafficking

About this item

Full title

Pathogen Effector Protein Screening in Yeast Identifies Legionella Factors That Interfere with Membrane Trafficking

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2005-03, Vol.102 (13), p.4866-4871

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Legionella pneumophila invades and replicates intracellularly in human and protozoan hosts. The bacteria use the Icm/Dot type IVB secretion system to translocate effectors that inhibit phagosome maturation and modulate host vesicle trafficking pathways. To understand how L. pneumophila modulates organelle trafficking in host cells, we carried out p...

Alternative Titles

Full title

Pathogen Effector Protein Screening in Yeast Identifies Legionella Factors That Interfere with Membrane Trafficking

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_102_13_4866_fulltext

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_102_13_4866_fulltext

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0501315102

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