NMR Study of a Membrane Protein in Detergent-Free Aqueous Solution
NMR Study of a Membrane Protein in Detergent-Free Aqueous Solution
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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One of the major obstacles to membrane protein (MP) structural studies is the destabilizing effect of detergents. Amphipols (APols) are short amphipathic polymers that can substitute for detergents to keep MPs water-soluble under mild conditions. In the present work, we have explored the feasibility of studying the structure of APol-complexed MPs b...
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NMR Study of a Membrane Protein in Detergent-Free Aqueous Solution
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TN_cdi_pnas_primary_102_25_8893
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_102_25_8893
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0503750102