Structure of the Kainate Receptor Subunit GluR6 Agonist-Binding Domain Complexed with Domoic Acid
Structure of the Kainate Receptor Subunit GluR6 Agonist-Binding Domain Complexed with Domoic Acid
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
We report the crystal structure of the glycosylated ligand-binding (S1S2) domain of the kainate receptor subunit GluR6, in complex with the agonist domoate. The structure shows the expected overall homology with AMPA and NMDA receptor subunit structures but reveals an unexpected binding mode for the side chain of domoate, in which contact is made t...
Alternative Titles
Full title
Structure of the Kainate Receptor Subunit GluR6 Agonist-Binding Domain Complexed with Domoic Acid
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pnas_primary_102_5_1708_fulltext
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_102_5_1708_fulltext
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0409573102