Rapid high-yield expression of full-size IgG antibodies in plants coinfected with noncompeting viral...
Rapid high-yield expression of full-size IgG antibodies in plants coinfected with noncompeting viral vectors
About this item
Full title
Author / Creator
Giritch, A , Marillonnet, S , Engler, C , Eldik, G. van , Botterman, J , Klimyuk, V and Gleba, Y
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Plant viral vectors allow expression of heterologous proteins at high yields, but so far, they have been unable to express heterooligomeric proteins efficiently. We describe here a rapid and indefinitely scalable process for high-level expression of functional full-size mAbs of the IgG class in plants. The process relies on synchronous coinfection...
Alternative Titles
Full title
Rapid high-yield expression of full-size IgG antibodies in plants coinfected with noncompeting viral vectors
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pnas_primary_103_40_14701
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_103_40_14701
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0606631103
