Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insul...
Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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Membrane microdomains (lipid rafts) are now recognized as critical for proper compartmentalization of insulin signaling. We previously demonstrated that, in adipocytes in a state of TNFα-induced insulin resistance, the inhibition of insulin metabolic signaling and the elimination of insulin receptors (IR) from the caveolae microdomains were associa...
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Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance
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TN_cdi_pnas_primary_104_34_13678_fulltext
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_104_34_13678_fulltext
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0703650104