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Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insul...

Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insul...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_104_34_13678_fulltext

Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance

About this item

Full title

Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2007-08, Vol.104 (34), p.13678-13683

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Membrane microdomains (lipid rafts) are now recognized as critical for proper compartmentalization of insulin signaling. We previously demonstrated that, in adipocytes in a state of TNFα-induced insulin resistance, the inhibition of insulin metabolic signaling and the elimination of insulin receptors (IR) from the caveolae microdomains were associa...

Alternative Titles

Full title

Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_104_34_13678_fulltext

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_104_34_13678_fulltext

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0703650104

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