Crystal Structure of the Helicobacter pylori Vacuolating Toxin p55 Domain
Crystal Structure of the Helicobacter pylori Vacuolating Toxin p55 Domain
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Publisher
National Academy of Sciences
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Language
English
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Publisher
National Academy of Sciences
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Contents
Helicobacter pylori VacA, a pore-forming toxin secreted by an autotransporter pathway, causes multiple alterations in human cells, contributes to the pathogenesis of peptic ulcer disease and gastric cancer, and is a candidate antigen for inclusion in an H. pylori vaccine. Here, we present a 2.4-Å crystal structure of the VacA p55 domain, which has...
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Full title
Crystal Structure of the Helicobacter pylori Vacuolating Toxin p55 Domain
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Record Identifier
TN_cdi_pnas_primary_104_41_16293
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_104_41_16293
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0707447104
