Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A
Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Before fertilization, vertebrate eggs are arrested in meiosis II by cytostatic factor (CSF), which holds the anaphase-promoting complex (APC) in an inactive state. It was recently reported that Mos, an integral component of CSF, acts in part by promoting the Rsk-mediated phosphorylation of the APC inhibitor Emi2/Erp1. We report here that Rsk phosph...
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Full title
Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A
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TN_cdi_pnas_primary_104_42_16564
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_104_42_16564
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0707537104