VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting...
VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
VEGF is the best characterized mediator of tumor angiogenesis. Anti-VEGF agents have recently demonstrated impressive efficacy in human cancer trials, but the optimal dosing of such agents must still be determined empirically, because biomarkers to guide dosing have yet to be established. The widely accepted (but unverified) assumption that VEGF pr...
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Full title
VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade
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TN_cdi_pnas_primary_104_47_18363
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_104_47_18363
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0708865104
