RCK1 high-affinity Ca²⁺ sensor confers carbon monoxide sensitivity to Slo1 BK channels
RCK1 high-affinity Ca²⁺ sensor confers carbon monoxide sensitivity to Slo1 BK channels
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Carbon monoxide (CO) is a lethal gas, but it is also increasingly recognized as a physiological signaling molecule capable of regulating a variety of proteins. Among them, large-conductance Ca²⁺- and voltage-gated K⁺ (Slo1 BK) channels, important in vasodilation and neuronal firing, have been suggested to be directly stimulated by CO. However, the...
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RCK1 high-affinity Ca²⁺ sensor confers carbon monoxide sensitivity to Slo1 BK channels
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TN_cdi_pnas_primary_105_10_4039
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_105_10_4039
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0800304105