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RCK1 high-affinity Ca²⁺ sensor confers carbon monoxide sensitivity to Slo1 BK channels

RCK1 high-affinity Ca²⁺ sensor confers carbon monoxide sensitivity to Slo1 BK channels

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_105_10_4039

RCK1 high-affinity Ca²⁺ sensor confers carbon monoxide sensitivity to Slo1 BK channels

About this item

Full title

RCK1 high-affinity Ca²⁺ sensor confers carbon monoxide sensitivity to Slo1 BK channels

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (10), p.4039-4043

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Carbon monoxide (CO) is a lethal gas, but it is also increasingly recognized as a physiological signaling molecule capable of regulating a variety of proteins. Among them, large-conductance Ca²⁺- and voltage-gated K⁺ (Slo1 BK) channels, important in vasodilation and neuronal firing, have been suggested to be directly stimulated by CO. However, the...

Alternative Titles

Full title

RCK1 high-affinity Ca²⁺ sensor confers carbon monoxide sensitivity to Slo1 BK channels

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_105_10_4039

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_105_10_4039

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0800304105

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