Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7
Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7
About this item
Full title
Author / Creator
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
VEGF has been shown to regulate endothelial cell (EC) proliferation and migration. However, the nuclear mediators of the actions of VEGF in ECs have not been fully defined. We show that VEGF induces the phosphorylation of three conserved serine residues in histone deacetylase 7 (HDAC7) via protein kinase D, which promotes nuclear export of HDAC7 an...
Alternative Titles
Full title
Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pnas_primary_105_22_7738
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_105_22_7738
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0802857105
