Starvation-dependent differential stress resistance protects normal but not cancer cells against hig...
Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Strategies to treat cancer have focused primarily on the killing of tumor cells. Here, we describe a differential stress resistance (DSR) method that focuses instead on protecting the organism but not cancer cells against chemotherapy. Short-term starved S. cerevisiae or cells lacking proto-oncogene homologs were up to 1,000 times better protected...
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Full title
Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy
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Record Identifier
TN_cdi_pnas_primary_105_24_8215_fulltext
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_105_24_8215_fulltext
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0708100105
