Synthetic glycopeptide vaccines combining β-mannan and peptide epitopes induce protection against ca...
Synthetic glycopeptide vaccines combining β-mannan and peptide epitopes induce protection against candidiasis
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
The first fully synthetic glycopeptide vaccines against a fungal disease have been used to combat disseminated candidiasis in mice. Six T cell peptides found in Candida albicans cell wall proteins were selected by algorithm peptide epitope searches; each was synthesized and conjugated to the fungal cell wall β-mannan trisaccharide [β-(Man)₃] by nov...
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Full title
Synthetic glycopeptide vaccines combining β-mannan and peptide epitopes induce protection against candidiasis
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Record Identifier
TN_cdi_pnas_primary_105_36_13526
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_105_36_13526
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0803195105
