Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy:...
Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: Blockade of compensatory renin increase
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Author / Creator
Zhang, Zhongyi , Zhang, Yan , Ning, Gang , Deb, Dilip K , Kong, Juan and Li, Yan Chun
Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The renin-angiotensin system (RAS) plays a critical role in the development of diabetic nephropathy, and blockade of the RAS is currently used for treatment of diabetic nephropathy. One major problem for the current RAS inhibitors is the compensatory renin increase, which reduces the efficacy of RAS inhibition. We have shown that vitamin D exerts r...
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Full title
Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: Blockade of compensatory renin increase
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TN_cdi_pnas_primary_105_41_15896
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_105_41_15896
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0803751105