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Conserved role for the Drosophila Pax6 homolog Eyeless in differentiation and function of insulin-pr...

Conserved role for the Drosophila Pax6 homolog Eyeless in differentiation and function of insulin-pr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_105_42_16183

Conserved role for the Drosophila Pax6 homolog Eyeless in differentiation and function of insulin-producing neurons

About this item

Full title

Conserved role for the Drosophila Pax6 homolog Eyeless in differentiation and function of insulin-producing neurons

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2008-10, Vol.105 (42), p.16183-16188

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Insulin/insulin-like growth factor (IGF) signaling constitutes an evolutionarily conserved pathway that controls growth, energy homeostasis, and longevity. In Drosophila melanogaster, key components of this pathway are the insulin-like peptides (Dilps). The major source of Dilps is a cluster of large neurons in the brain, the insulin-producing cell...

Alternative Titles

Full title

Conserved role for the Drosophila Pax6 homolog Eyeless in differentiation and function of insulin-producing neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_105_42_16183

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_105_42_16183

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0708330105

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