Bilirubin and glutathione have complementary antioxidant and cytoprotective roles
Bilirubin and glutathione have complementary antioxidant and cytoprotective roles
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United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
Glutathione (GSH) and bilirubin are prominent endogenous antioxidant cytoprotectants. Despite tissue levels that are thousands of times lower than GSH, bilirubin is effective because of the biosynthetic cycle wherein it is generated from biliverdin by biliverdin reductase (BVR). When bilirubin acts as an antioxidant, it is oxidized to biliverdin, w...
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Full title
Bilirubin and glutathione have complementary antioxidant and cytoprotective roles
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TN_cdi_pnas_primary_106_13_5171
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_13_5171
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0813132106