Log in to save to my catalogue

Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadh...

Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadh...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_14_5575

Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23

About this item

Full title

Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (14), p.5575-5580

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The hereditary hearing-vision loss disease Usher syndrome (USH) is caused by defects in several proteins, most of which form an integrated protein network called Usher interactome. Harmonin/Ush1C is a master scaffold in the assembly of the Usher protein complexes, because harmonin is known to bind to every protein in the Usher interactome. However,...

Alternative Titles

Full title

Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_106_14_5575

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_14_5575

Other Identifiers

ISSN

0027-8424,1091-6490

E-ISSN

1091-6490

DOI

10.1073/pnas.0901819106

How to access this item