Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadh...
Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23
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Author / Creator
Pan, Lifeng , Yan, Jing , Wu, Lin and Zhang, Mingjie
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
The hereditary hearing-vision loss disease Usher syndrome (USH) is caused by defects in several proteins, most of which form an integrated protein network called Usher interactome. Harmonin/Ush1C is a master scaffold in the assembly of the Usher protein complexes, because harmonin is known to bind to every protein in the Usher interactome. However,...
Alternative Titles
Full title
Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23
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Record Identifier
TN_cdi_pnas_primary_106_14_5575
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_14_5575
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ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.0901819106