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Non-competitive androgen receptor inhibition in vitro and in vivo

Non-competitive androgen receptor inhibition in vitro and in vivo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_17_7233_fulltext

Non-competitive androgen receptor inhibition in vitro and in vivo

About this item

Full title

Non-competitive androgen receptor inhibition in vitro and in vivo

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-04, Vol.106 (17), p.7233-7238

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Androgen receptor (AR) inhibitors are used to treat multiple human diseases, including hirsutism, benign prostatic hypertrophy, and prostate cancer, but all available anti-androgens target only ligand binding, either by reduction of available hormone or by competitive antagonism. New strategies are needed, and could have an important impact on ther...

Alternative Titles

Full title

Non-competitive androgen receptor inhibition in vitro and in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_106_17_7233_fulltext

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_17_7233_fulltext

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0807282106

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