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Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells

Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_26_10734_fulltext

Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells

About this item

Full title

Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (26), p.10734-10739

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The ability to induce durable transplantation tolerance predictably and consistently in the clinic is a highly desired but elusive goal. Progress is hampered by lack of appropriate experimental models in which to study resistance to transplantation tolerance. Here, we demonstrate that T helper 1-associated T box 21 transcription factor (Tbet) KO re...

Alternative Titles

Full title

Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_106_26_10734_fulltext

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_26_10734_fulltext

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0812538106

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