Positive selection optimizes the number and function of MHCII-restricted CD4⁺ T cell clones in the n...
Positive selection optimizes the number and function of MHCII-restricted CD4⁺ T cell clones in the naive polyclonal repertoire
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
T cell receptors (TCRs) on T lymphocytes in an individual bind foreign peptides bound to major histocompatibility complex (MHC) molecules expressed in that individual (designated MHCA). Results from radiation bone marrow chimeras and TCR transgenic mice indicate that this complex form of antigen recognition is the result of positive selection of cl...
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Full title
Positive selection optimizes the number and function of MHCII-restricted CD4⁺ T cell clones in the naive polyclonal repertoire
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TN_cdi_pnas_primary_106_27_11241_fulltext
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_27_11241_fulltext
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0902015106
