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Circulating CD21low B cells in common variable immunodeficiency resemble tissue homing, innate-like...

Circulating CD21low B cells in common variable immunodeficiency resemble tissue homing, innate-like...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_32_13451

Circulating CD21low B cells in common variable immunodeficiency resemble tissue homing, innate-like B cells

About this item

Full title

Circulating CD21low B cells in common variable immunodeficiency resemble tissue homing, innate-like B cells

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (32), p.13451-13456

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

The homeostasis of circulating B cell subsets in the peripheral blood of healthy adults is well regulated, but in disease it can be severely disturbed. Thus, a subgroup of patients with common variable immunodeficiency (CVID) presents with an extraordinary expansion of an unusual B cell population characterized by the low expression of CD21. CD21lo...

Alternative Titles

Full title

Circulating CD21low B cells in common variable immunodeficiency resemble tissue homing, innate-like B cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pnas_primary_106_32_13451

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_32_13451

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0901984106

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