human IgM pentamer is a mushroom-shaped molecule with a flexural bias
human IgM pentamer is a mushroom-shaped molecule with a flexural bias
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Contents
The textbook planar model of pentameric IgM, a potent activator of complement C1q, is based upon the crystallographic structure of IgG. Although widely accepted, key predictions of this model have not yet been directly confirmed, which is particularly important since IgG lacks a major Ig fold domain in its Fc region that is present in IgM. Here, we...
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Full title
human IgM pentamer is a mushroom-shaped molecule with a flexural bias
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Record Identifier
TN_cdi_pnas_primary_106_35_14960
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pnas_primary_106_35_14960
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0903805106
